Latest News

How Calibration for Instrumentation Impacts the Life Science Vertical


The calibration of tools and equipment is critical to the life science industry. The professionals who work within this sector require safe and accurate tools when they travel into the field or work under strict requirements in the lab.

The calibration process ensures life sciences manufacturers can trust the tools and equipment they use every day. With properly calibrated equipment, the chances of mistakes or errors will be drastically reduced. Appropriate equipment calibration also helps to lower the cost of manufacturing and production—when product quality is ensured during manufacturing, it mitigates the risk of repeated defects in production runs.

Calibration utilizes the scientific method to help predict impending miscalculations, allowing specialists to correct any errors identified during the process. Calibrating equipment economizes labor, time, and other production resources because it verifies product quality before it's too late to fix mistakes.

Calibration is beneficial to researchers and other life science professionals. Scientists and researchers need a set of reliable methods for accurate testing. As such, life science companies are required to perform a host of regular calibrations on their instrumentation in order to meet regulations. These processes can be costly, but modern instrumentation serves to simplify the process.

Legal Requirements for Calibration Instrumentation

ISO9001:2008-7.6, GMP, and WHO regulations and standards require that equipment and instrumentation be calibrated or verified at specific intervals. During these calibrations, equipment must be measured against strict standards that are easily-traceable to both national and international standards.

Plant operators should always remember that the responsibility of setting up and executing maintenance programs falls on their shoulders. The operational budget should always be a concern, and extending the time between calibrations may seem like an appealing way to achieve cost savings. However, plant operators also need to consider how far they can push calibrations before reliability and quality are sacrificed.

Once an instrument has been installed and has operated in normal working order for a time, the first recalibration step will offer insight as to whether that instrument is still operating within specifications. During checks like these, failed "as-found" problems are critical. These issues must be further investigated in case of possible impact on product quality.

Where to Calibrate

Calibration should always occur within accredited calibration labs when possible. Accredited facilities will be certified by ISO/IEC 17025 and ISO/IEC 17025 A2LA standards and be able to provide up-to-date documentation verifying such.

If an organization doesn't have access to a calibration lab or instrumentation is too cumbersome to move, calibration services can be conducted on site by certified professionals using a portable flow rig. These rigs don't offer the same level of accuracy that’s found in a certified calibration lab, but they can still calibrate instruments within tolerances of at least +/-0.25%. The accuracy of a portable flow rig depends largely on the type of equipment being calibrated.

Portable flow rigs offer companies provide convenience and work quickly. Depending on a plant's layout, it's possible for several measuring points to be calibrated in a short period of time.

Endress+Hauser regularly offers reliable, efficient calibration services to clients in the life science industry. To learn more about Endress+Hauser's calibration services, please review this case study detailing the calibration support we provide to a major pharmaceutical supplier.


...Read More

Using Electromagnetic Flowmeters in the Wastewater Industry

Wastewater treatment facilities must effectively filter toxins and pathogens from inflowing water to produce high-quality drinking water. They do so via complex operational processes that involve a wide range of flow measurement tasks.

...Read More

Why OPP?

Overfill prevention processes (OPPs) act as a subset of the safety management system (SMS) that companies use to maintain the health of their workers and equipment. SMS, broadly defined, encompasses all the safety concerns for any processes, equipment, and systems within an organization or facility.

...Read More

The Value of Automation and Instrumentation in the Oil and Gas Industry

Oil and gas producers rely on process automation and instrumentation to drive down costs and maintain employee safety. These industries operate via several complicated and laborious processes that are dangerous to human personnel, making it important to consider ways new technology can alleviate these pressures. Automation and instrumentation processes also help make oil and gas wells in remote parts of the world profitable despite operating in severe conditions.

...Read More

Endress+Hauser Is Coming Out With a New Look

The team at Endress+Hauser is excited to announce that we’re overhauling our website to make it more responsive, user-friendly, and aesthetically pleasing. This means it’ll soon be easier than ever to access our product information, documentation, educational content, and more.

...Read More

When to Use Pressure Switches

Pressure switches use fluid pressure to close off electrical contact when it reaches its input. Industries use pressure switches to control and supervise systems that require pressurized fluids to function.

...Read More

A Recap of Endress+Hauser’s Attendance at the 2018 Automation Fair

The 2018 Automation Fair in Philadelphia was an exciting gathering of leaders in today's industrial automation industry. In its 27th year, the Automation Fair trade show consistently showcases new technologies; connects innovators, creators, and problem-solvers; and offers countless ways to expand the possibilities of industrial manufacturing.

...Read More

Endress+Hauser Hosts the 5th CCEF Introducing Students to Technical Fields

Endress+Hauser has long promoted the growth and development of careers in process-automation trades by partnering with local schools to bolster STEM education. Recently, we hosted the 5th Annual Community+Career and Education Forum (CCEF) with contributions from Central Nine Career Center and Aspire Johnson County. This event seeks to inspire local students to learn more about all that STEM careers have to offer.

"The kids are so excited to show how smart they are. I like to think they leave this activity knowing they have a lot to contribute to the world," said Michael Robinson, a forum volunteer.

Many in the community expressed similar sentiments. "The thank-you cards, emails, and people stopping us in the community to show appreciation—it's been amazing and humbling to see and feel the gratitude from parents, students, and educators," said Brandyn Ferguson, Vice President of Human Resources.

We spend 11 months of the year planning this celebrated forum, which took place on September 20, 2018. The event was a resounding success, bringing more than 1,000 students, educators, parents, volunteers, and community leaders to our Indiana facility. 

...Read More

Introducing Endress+Hauser’s Memosens CCS50D Chlorine Dioxide Sensor

Chlorine dioxide is a chemical compound that appears as a red-to-yellowish-green gas at room temperature. It readily dissolves in water and is typically used as a disinfecting agent, especially in the water treatment industry. However, excessive amounts of chlorine dioxide in potable water supplies can be harmful to consumers. Therefore, compliance with water quality industry standards is of utmost importance.

Endress+Hauser’s Memosens CCS50D is a durable, low maintenance sensor specifically designed to ensure safe and efficient dosages of chlorine dioxide in almost any industrial application. Memosens technology works by converting the measured chlorine dioxide level and converting it to a digital signal which is then transferred inductively to a transmitter.

...Read More

Instrument Technology Moves into Process Development Laboratories

Calibration of measurement instruments is essential to ensuring that the device performs as per its original specifications, thus avoiding measurement inaccuracy and guaranteeing reliable and repeatable results. The process of calibration typically involves verifying, or configuring the performance of an instrument by using it to test samples of one or more known values.

In the life sciences field, regulatory authorities have imposed strict guidelines on the calibration and verification of measurement devices. Typically, compliance is required to be checked at all stages of the drug development process from process development to large-scale manufacturing. Different sensors used at each phase of the process require separate calibration procedures and records.

However, technological advancements in modern measurement instruments have made it possible to use the same apparatus at all stages of the development process – simplifying regulatory record-keeping and facilitating ease of calibration, compliance, and verification.

...Read More


Recommended Resources for You

Reduce Inventory Costs
Calibration Guide
Water Recovery Case Study